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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TP53BP1 All Species: 13.03
Human Site: Y945 Identified Species: 47.78
UniProt: Q12888 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12888 NP_001135451.1 1972 213574 Y945 T P I G I S N Y P E S T I A T
Chimpanzee Pan troglodytes XP_001158270 1972 213535 Y945 T P I G I S N Y P E S T I A T
Rhesus Macaque Macaca mulatta XP_001107220 1972 213653 Y945 T P I G I S N Y P E S T I A A
Dog Lupus familis XP_849774 1976 214088 Y949 T P I D I S N Y P E S T I A T
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001082071 2104 231430 A1050 N I S V D N S A E E A R E A D
Zebra Danio Brachydanio rerio NP_001073639 1709 184731 K724 K G K S P P F K S S S Q P V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798355 2169 238737 K1058 T S A A V T L K T K R T P K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 89.2 N.A. N.A. N.A. N.A. N.A. N.A. 36.9 34.4 N.A. N.A. N.A. N.A. 20.5
Protein Similarity: 100 99.5 98.2 93.6 N.A. N.A. N.A. N.A. N.A. N.A. 54.5 51.3 N.A. N.A. N.A. N.A. 37.6
P-Site Identity: 100 100 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 13.3 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 33.3 13.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 15 0 0 0 15 0 0 15 0 0 72 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 15 15 0 0 0 0 0 0 0 0 0 15 % D
% Glu: 0 0 0 0 0 0 0 0 15 72 0 0 15 0 0 % E
% Phe: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 43 0 0 0 0 0 0 0 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 58 0 58 0 0 0 0 0 0 0 58 0 0 % I
% Lys: 15 0 15 0 0 0 0 29 0 15 0 0 0 15 0 % K
% Leu: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 0 0 0 15 58 0 0 0 0 0 0 0 0 % N
% Pro: 0 58 0 0 15 15 0 0 58 0 0 0 29 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 15 15 0 0 0 % R
% Ser: 0 15 15 15 0 58 15 0 15 15 72 0 0 0 15 % S
% Thr: 72 0 0 0 0 15 0 0 15 0 0 72 0 0 43 % T
% Val: 0 0 0 15 15 0 0 0 0 0 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _